Cam choice is very subjective and depends on how you like your engine to idle (smooth as glass, lopey, chopy, or somewhere in between)- talk to your builder and he can suggest some grinds for you. If you need good vacuum for power brakes I recommend you stay w/ a cam that has a 112-114 LSA (lope separation angle), as these tend to idle smoother and have more vacuum, despite having wider duration and more lift than stock. Your 400 w/ no.16 heads has a small combustion chamber (72cc) and makes 10:1 SCR- a cam w/ an advertised duration of around 280-290 degrees will take advantage of this higher compression.
And as far as carbs are concerned, I've run Holleys for most of the 30+ years I've been into Firebirds and T/A's- if you have a bad Holley that's nor running well, it's most likely due to poor carb choice, needs a rebuild, or lack of knowledge on the rebuilder. A single feed 600 cfm 4-bbl. Holley is a poor choice for a 400- a dual-feed 750 cfm vacuum secondary will make a better all-around carb and can be tuned to deliver reasonable fuel economy as well. Holleys and Holley-type carbs are used in professional racing because they work- a good carb and ignition tune will also prove it to be an excellent performance carb. Q-Jets are also good carbs, but must be properly rebuilt to function well and offer huge secondaries which deliver great performance as well. The E-carbs are decent as far as bolt-on performers go, but their side-mounted fuel bowls will limit performance.
Geno